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Clinical and histopathological study on the effect of Nonresorbable membrane with Demineralized freeze dried bone graft for Guided Bone Regeneration in Implant Dehiscence Defects

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Abstract


The purpose of this study is to examine the effect of non-resorbable membrane such as
e-PTFE which was used with DFDB in bone regeneration on dehiscence defect in peri-implant
area.
Amomg the patients, who have recieved an implant surgery at the department of
Periodontics in Dan Kook University Dental Hospital, 12 patients showed implant exposure
due to the dehiscence defect and 15 implants of these 22 patients were the target of the
treatment.
Periodontists randomly applied Gore-Tex¨Þ
to the patients and treated them with antibiotics
for five days both preoperatively and postoperatively. Reentry period was 26 weeks on average
in maxilla and 14 weeks on average in mandible.
The results were as follows :
1. Dehiscence bone defect frequently appeared in premolar in mandible and anterior teeth in
maxilla respectively.
2. Among 15 cases, 1 membrane exposure was observed and in this case, regenerated area
was decreased.
3. In non-resorbable membrane, bone surface area 9.25¡¾4.84 preoperatively and significantly
increased to 11.48¡¾7.52 postoperatively(P<0.05).
4. The increase of bone surface area in non-resorbable membrane was 2.23¡¾3.38.
5. As a result of histopathological finding, DFDB surrounded by new bone formation and
lamellate bone, resorption of DFDB and bone mineralization was found. Also, fibrosis of
connective tissue beneath the membrane was found.
This study shows that the surgical method using DFDB and non-resorbable membrane on
dehiscence defect in peri-implant area is effective in bone regeneration.2)

Å°¿öµå

bone graft;guided bone regeneration;implant dehiscence defects

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